2009

Liu, L., Koharudin, L.M., Gronenborn, A.M., Bahar, I. (2009). A comparative analysis of the equilibrium dynamics of a designed protein inferred from NMR, X-ray, and computations. Proteins. 77, 927-39

Shaffer, J. M. and Smithgall, T. E. (2009) Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer. Genes Chromosomes Cancer. 48, 272-284

Daghestani, H.N., Fernig, D.G., and Day, B.W. (2009) Evaluation of biosensor surfaces for the evaluation of microtubule perturbation. Biosensors and Bioelectronics, 25, 136-41

Myint, W. Gong, Q. Ishima, R. (2009) Practical Aspects of 15N CPMG Transverse Relaxation Experiments for Proteins in Solution. Concepts in Magnetic Resonance Part A. 34A, 63-75. 

Myint, W. Ishima, R. (2009) Chemical exchange effects during refocusing pulses in constant-time CPMG relaxation dispersion experiments. J Biomol NMR. 45, 207-216

Thakur, A.K., Jayaraman, M., Mishra, R., Thakur, M., Chellgren, M.V., Byeon, I.L., Anjum, D.H., Kodali, R., Creamer, T.P., Conway, J.F., Gronenborn, A.M., Wetzel, R. (2009) Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nat Struct Mol Biol 16(4), 380-389.

2008

Iyer, A. K., Tran, K. T., Griffith, L. and Wells, A. (2008) Cell surface restriction of EGFR by a tenascin cytotactin-encoded EGF-like repeat is preferential for motility-related signaling. Journal of Cellular Physiology. 214, 504-512

Isin, B., Schulten, K., Tajkhorshid, E. and Bahar, I. (2008) Mechanism of Signal Propagation upon Retinal Isomerization: Insights from Molecular Dynamics Simulations of Rhodopsin Restrained by Normal Modes. Biophys J

Rubenstein, E. M., McCartney, R. R., Zhang, C., Shokat, K. M., Shirra, M. K., Arndt, K. M. and Schmidt, M. C. (2008) Snf1 activation loop phosphorylation is controlled by availability of the phosphorylated threonine 210 to the PP1 phosphatase. J Biol Chem. 283, 222-230

Lewarchik, C. M., Peters, K. W., Qi, J. and Frizzell, R. A. (2008) Regulation of CFTR trafficking by its R domain. J Biol Chem. 283, 28401-28412

Guerriero, C. J., Lai, Y. and Weisz, O. A. (2008) Differential sorting and Golgi export requirements for raft-associated and raft-independent apical proteins along the biosynthetic pathway. J Biol Chem. 283, 18040-18047

Miedel, M. T., Rbaibi, Y., Guerriero, C. J., Colletti, G., Weixel, K. M., Weisz, O. A. and Kiselyov, K. (2008) Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesis. J Exp Med. 205, 1477-1490

Miedel, M. T., Rbaibi, Y., Guerriero, C. J., Colletti, G., Weixel, K. M., Weisz, O. A. and Kiselyov, K. (2008) Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesis. J Exp Med. 205, 1477-1490

Nakao, A., Kaczorowski, D.J., Zuckerbraun, B.S., Lei, J., Faleo, G., Deguchi, K., McCurry, K.R., Billiar, T.R., Kanno, S. (2008) Galantamine and carbon monoxide protect brain microvascular endothelial cells by heme oxygenase-1 induction. Biochem Biophys Res Commun. 367, 674-9

He, X., Zhu, Z., Johnson, C., Stoops, J., Eaker, A. E., Bowen, W. and DeFrances, M. C. (2008) PIK3IP1, a negative regulator of PI3K, suppresses the development of hepatocellular carcinoma. Cancer Res. 68, 5591-5598

Horzempa, J., Carlson, P. E., Jr., O'Dee, D. M., Shanks, R. M. and Nau, G. J. (2008) Global transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis. BMC Microbiol. 8, 172

Horzempa, J., Tarwacki, D. M., Carlson, P. E., Jr., Robinson, C. M. and Nau, G. J. (2008) Characterization and application of a glucose-repressible promoter in Francisella tularensis. Appl Environ Microbiol. 74, 2161-2170

de Souza, A. J., Oak, J. S., Jordanhazy, R., Dekruyff, R. H., Fruman, D. A. and Kane, L. P. (2008) T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase. J Immunol. 180, 6518-6526

Krishnamoorthy, N., Oriss, T. B., Paglia, M., Fei, M., Yarlagadda, M., Vanhaesebroeck, B., Ray, A. and Ray, P. (2008) Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma. Nat Med

Sheridan, B. S., Cherpes, T. L., Urban, J., Kalinski, P. and Hendricks, R. L. (2008) Reevaluating the CD8 T cell response to HSV-1: Involvement of CD8 T cells reactive to subdominant epitopes. J Virol

Cherpes, T. L., Busch, J. L., Sheridan, B. S., Harvey, S. A. and Hendricks, R. L. (2008) Medroxyprogesterone acetate inhibits CD8+ T cell viral-specific effector function and induces herpes simplex virus type 1 reactivation. J Immunol. 181, 969-975

Hughes, J. L., Nolder, C. L., Nowalk, A. J., Clifton, D. R., Howison, R. R., Schmit, V. L., Gilmore, R. D., Jr. and Carroll, J. A. (2008) Borrelia burgdorferi surface-localized proteins expressed during persistent murine infection are conserved among diverse Borrelia spp. Infect Immun

Vogt, A., McDonald, P. R., Tamewitz, A., Sikorski, R. P., Wipf, P., Skoko, J. J., 3rd and Lazo, J. S. (2008) A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells. Mol Cancer Ther. 7, 330-340

Knickelbein, J. E., Khanna, K. M., Yee, M. B., Baty, C. J., Kinchington, P. R. and Hendricks, R. L. (2008) Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency. Science. 322, 268-271

Ramachandran, S., Knickelbein, J. E., Ferko, C., Hendricks, R. L. and Kinchington, P. R. (2008) Development and pathogenic evaluation of recombinant herpes simplex virus type 1 expressing two fluorescent reporter genes from different lytic promoters. Virology. 378, 254-264

Rapaka, R. R. and Kolls, J. K. (2008) Pathogenesis of allergic bronchopulmonary aspergillosis in cystic fibrosis: current understanding and future directions. Med Mycol, 1-7

Mattila, P. E., Metz, A. E., Rapaka, R. R., Bauer, L. D. and Steele, C. (2008) Dectin-1 Fc targeting of aspergillus fumigatus beta-glucans augments innate defense against invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 52, 1171-1172

Chandra, D., Werner, D. F., Liang, J., Suryanarayanan, A., Harrison, N. L., Spigelman, I., Olsen, R. W. and Homanics, G. E. (2008) Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice. Alcohol Clin Exp Res. 32, 10-18

Ma, D., Brandon, N. R., Cui, T., Bondarenko, V., Canlas, C., Johansson, J. S., Tang, P., Xu, Y. (2008) Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses. Biophys J. 94, 4454-63

Cui, T., Bondarenko, V., Ma, D., Canlas, C., Brandon, N.R., Johansson, J.S., Xu, Y., Tang, P. (2008) Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics. Biophys J. 94, 4464-72

2007

Harrison, S. J., Nishinakamura, R. and Monaghan, A. P. (2007) Sall1 Regulates Mitral Cell Development and Olfactory Nerve Extension in the Developing Olfactory Bulb. Cereb Cortex, doi:10.1093/cercor/bhm191

Martinez, I., Wang, J., Hobson, K. F., Ferris, R. L. and Khan, S. A. (2007) Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas. Eur J Cancer. 43, 415-432

Balestreire, E. M. and Apodaca, G. (2007) Apical epidermal growth factor receptor signaling: regulation of stretch-dependent exocytosis in bladder umbrella cells. Molecular biology of the cell. 18, 1312-1323

Li, R., Boehm, A. L., Miranda, M. B., Shangary, S., Grandis, J. R. and Johnson, D. E. (2007) Targeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells. Neoplasia (New York, N.Y. 9, 801-811

Quesnelle, K. M., Boehm, A. L. and Grandis, J. R. (2007) STAT-mediated EGFR signaling in cancer. Journal of Cellular Biochemistry. 102, 311-319

Pflug, B. R., Zheng, H., Udan, M. S., D'Antonio, J. M., Marshall, F. F., Brooks, J. D. and Nelson, J. B. (2007) Endothelin-1 promotes cell survival in renal cell carcinoma through the ET(A) receptor. Cancer letters. 246, 139-148

Godara, G., Pecher, S., Jukic, D. M., D'Antonio, J. M., Akhavan, A., Nelson, J. B. and Pflug, B. R. (2007) Distinct patterns of endothelin axis expression in primary prostate cancer. Urology. 70, 209-215

Iyer, A. K., Tran, K. T., Borysenko, C. W., Cascio, M., Camacho, C. J., Blair, H. C., Bahar, I. and Wells, A. (2007) Tenascin cytotactin epidermal growth factor-like repeat binds epidermal growth factor receptor with low affinity. Journal of Cellular Physiology. 211, 748-758

Yue, W., Dacic, S., Sun, Q., Landreneau, R., Guo, M., Zhou, W., Siegfried, J. M., Yu, J. and Zhang, L. (2007) Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. Clin Cancer Res. 13, 4336-4344

O'Keefe, S. J., Stevens, S., Lee, R., Zhou, W. and Zfass, A. (2007) Physiological evaluation of the severity of pancreatic exocrine dysfunction during endoscopy. Pancreas. 35, 30-36

Craigo, J. K., Durkin, S., Sturgeon, T. J., Tagmyer, T., Cook, S. J., Issel, C. J. and Montelaro, R. C. (2007) Immune suppression of challenged vaccinates as a rigorous assessment of sterile protection by lentiviral vaccines. Vaccine. 25, 834-845

Ghosh, H. S., Spencer, J. V., Ng, B., McBurney, M. W. and Robbins, P. D. (2007) Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription. Biochem J. 408, 105-111

Pillemer, B. B., Xu, H., Oriss, T. B., Qi, Z. and Ray, A. (2007) Deficient SOCS3 expression in CD4+CD25+FoxP3+ regulatory T cells and SOCS3-mediated suppression of Treg function. European Journal of Immunology. 37, 2082-2089

Bansal, P. and Lazo, J. S. (2007) Induction of Cdc25B regulates cell cycle resumption after genotoxic stress. Cancer Research. 67, 3356-3363

Srivastava, S. K., Bansal, P., Oguri, T., Lazo, J. S. and Singh, S. V. (2007) Cell division cycle 25B phosphatase is essential for benzo(a)pyrene-7,8-Diol-9,10-epoxide induced neoplastic transformation. Cancer Research. 67, 9150-9157

Beriwal, S., Gan, G. N., Heron, D. E., Selvaraj, R. N., Kim, H., Lalonde, R., Kelley, J. L. and Edwards, R. P. (2007) Early clinical outcome with concurrent chemotherapy and extended-field, intensity-modulated radiotherapy for cervical cancer. International Journal of Radiation Oncology, Biology, Physics. 68, 166-171

Gong, H., Guo, P., Zhai, Y., Zhou, J., Uppal, H., Jarzynka, M. J., Song, W. C., Cheng, S. Y. and Xie, W. (2007) Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor. Molecular Endocrinology. 21, 1781-1790

Uppal, H., Saini, S. P., Moschetta, A., Mu, Y., Zhou, J., Gong, H., Zhai, Y., Ren, S., Michalopoulos, G. K., Mangelsdorf, D. J. and Xie, W. (2007) Activation of LXRs prevents bile acid toxicity and cholestasis in female mice. Hepatology. 45, 422-432

Ferguson, C., Hardy, S. L., Werner, D. F., Hileman, S. M., Delorey, T. M. and Homanics, G. E. (2007) New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout. BMC Neuroscience. 8, 85

McClane, B. A. (2007) Compositional and stoichiometric analysis of Clostridium perfringens enterotoxin complexes in Caco-2 cells and claudin 4 fibroblast transfectants. Cellular Microbiology. 9, 2734-2755

Smedley, J. G., 3rd, Uzal, F. A. and McClane, B. A. (2007) Identification of a prepore large-complex stage in the mechanism of action of Clostridium perfringens enterotoxin. Infection and Immunity. 75, 2381-2390

Oztan, A., Silvis M, Weisz OA, Bradbury N, Hsu SC, Goldenring J, Yeaman C, Apodaca G. (2007) Exocyst Requirement for Endocytic Traffic Directed Toward the Apical Pole of Polarized MDCK Cells. Mol Biol Cell. 18, 3978-92

Ducharme N, Williams JA, Oztan, A., Apodaca G, Goldenring JR. (2007) Dominant negative Rab11-FIP2 mutants uncover differentiable steps in the apical recycling pathway. Am J Physiol Cell Physiol. 293, C1059-72

Cresawn KO, Potter BA, Oztan, A., Guerriero CJ, Ihrke G, Goldenring JR, Apodaca G, Weisz OA. (2007) Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins. EMBO J. 26, 3737-48

Cresawn, K. O., Potter, B. A., Oztan, A., Guerriero, C. J., Ihrke, G., Goldenring, J. R., Apodaca, G. and Weisz, O. A. (2007) Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins. Embo J. 26, 3737-3748

Guerriero, C. J. and Weisz, O. A. (2007) N-WASP inhibitor wiskostatin nonselectively perturbs membrane transport by decreasing cellular ATP levels. Am J Physiol Cell Physiol. 292, C1562-1566

Weixel, K. M., Edinger, R. S., Kester, L., Guerriero, C. J., Wang, H., Fang, L., Kleyman, T. R., Welling, P. A., Weisz, O. A. and Johnson, J. P. (2007) Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells. J Biol Chem. 282, 36534-36542

Tatro, E.T., Everall, I.P., Kaul, M., Achim, C.L. (2009) Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: Implications for major depressive disorder. Brain Research, 1286, 1-12.

Zhu, Z., He, X., Johnson, C., Stoops, J., Eaker, A. E., Stoffer, D. S., Bell, A., Zarnegar, R. and DeFrances, M. C. (2007) PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein. Biochem Biophys Res Commun. 358, 66-72

Tian, F., Grimaldo, S., Fujita, M., Cutts, J., Vujanovic, N. L. and Li, L. Y. (2007) The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation. J Immunol. 179, 3742-3751

Lui, V. W., Boehm, A. L., Koppikar, P., Leeman, R. J., Johnson, D., Ogagan, M., Childs, E., Freilino, M. and Grandis, J. R. (2007) Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1. Mol Pharmacol. 71, 1435-1443

Goding, S. R., Yang, Q., Knudsen, K. B., Potter, D. M. and Basse, P. H. (2007) Cytokine gene therapy using adenovirally transduced, tumor-seeking activated natural killer cells. Hum Gene Ther. 18, 701-711

Carlson, P. E., Jr., Carroll, J. A., O'Dee, D. M. and Nau, G. J. (2007) Modulation of virulence factors in Francisella tularensis determines human macrophage responses. Microb Pathog. 42, 204-214

Sheridan, B. S., Knickelbein, J. E. and Hendricks, R. L. (2007) CD8 T cells and latent herpes simplex virus type 1: keeping the peace in sensory ganglia. Expert Opin Biol Ther. 7, 1323-1331

Freeman, M. L., Sheridan, B. S., Bonneau, R. H. and Hendricks, R. L. (2007) Psychological stress compromises CD8+ T cell control of latent herpes simplex virus type 1 infections. J Immunol. 179, 322-328

Plessner, H. L., Lin, P. L., Kohno, T., Louie, J. S., Kirschner, D., Chan, J. and Flynn, J. L. (2007) Neutralization of tumor necrosis factor (TNF) by antibody but not TNF receptor fusion molecule exacerbates chronic murine tuberculosis. J Infect Dis. 195, 1643-1650

Lin, P. L., Plessner, H. L., Voitenok, N. N. and Flynn, J. L. (2007) Tumor necrosis factor and tuberculosis. J Investig Dermatol Symp Proc. 12, 22-25

Caltagarone, J., Jing, Z. and Bowser, R. (2007) Focal adhesions regulate Abeta signaling and cell death in Alzheimer's disease. Biochim Biophys Acta. 1772, 438-445

Knickelbein, J. E., Divito, S. and Hendricks, R. L. (2007) Modulation of CD8+ CTL effector function by fibroblasts derived from the immunoprivileged cornea. Invest Ophthalmol Vis Sci. 48, 2194-2202

Sheridan, B. S., Knickelbein, J. E. and Hendricks, R. L. (2007) CD8 T cells and latent herpes simplex virus type 1: keeping the peace in sensory ganglia. Expert Opin Biol Ther. 7, 1323-1331

Glykys J, Peng Z, Chandra, D., Homanics GE, Houser CR, Mody I (2007) A novel naturally occuring GABAA receptor partnership with high sensitivity to ethanol. Nature Neuroscience 10:40-48

Brisson, M., Foster, C., Wipf, P., Joo, B., Tomko, R. J., Jr., Nguyen, T. and Lazo, J. S. (2007) Independent mechanistic inhibition of cdc25 phosphatases by a natural product caulibugulone. Mol Pharmacol. 71, 184-192

Rapaka, R. R., Goetzman, E. S., Zheng, M., Vockley, J., McKinley, L., Kolls, J. K. and Steele, C. (2007) Enhanced defense against Pneumocystis carinii mediated by a novel dectin-1 receptor Fc fusion protein. J Immunol. 178, 3702-3712

2006

Bagci, E. Z., Vodovotz, Y., Billiar, T. R., Ermentrout, G. B. and Bahar, I. (2006) Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores. Biophysical Journal. 90, 1546-1559

Borysenko, C. W., Garcia-Palacios, V., Griswold, R. D., Li, Y., Iyer, A. K., Yaroslavskiy, B. B., Sharrow, A. C. and Blair, H. C. (2006) Death receptor-3 mediates apoptosis in human osteoblasts under narrowly regulated conditions. Journal of Cellular Physiology. 209, 1021-1028

Zhou, W., Grandis, J. R. and Wells, A. (2006) STAT3 is required but not sufficient for EGF receptor-mediated migration and invasion of human prostate carcinoma cell lines. British Journal of Cancer. 95, 164-171

O'Keefe S, J., Lee, R. B., Li, J., Zhou, W., Stoll, B. and Dang, Q. (2006) Trypsin and splanchnic protein turnover during feeding and fasting in human subjects. American Journal of Physiology. 290, G213-221

Tomko, R. J., Jr., Bansal, P. and Lazo, J. S. (2006) Airing out an antioxidant role for the tumor suppressor p53. Molecular Interventions. 6, 23-25, 22

Zhou, J., Zhai, Y., Mu, Y., Gong, H., Uppal, H., Toma, D., Ren, S., Evans, R. M. and Xie, W. (2006) A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway. The Journal of Biological Chemistry. 281, 15013-15020

Werner, D. F., Blednov, Y. A., Ariwodola, O. J., Silberman, Y., Logan, E., Berry, R. B., Borghese, C. M., Matthews, D. B., Weiner, J. L., Harrison, N. L., Harris, R. A. and Homanics, G. E. (2006) Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. The Journal of Pharmacology and Experimental Therapeutics. 319, 219-227

Chandra, D., Jia, F., Liang, J., Peng, Z., Suryanarayanan, A., Werner, D. F., Spigelman, I., Houser, C. R., Olsen, R. W., Harrison, N. L. and Homanics, G. E. (2006) GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol. Proceedings of the National Academy of Sciences of the United States of America. 103, 15230-15235

Isin, B., Rader, A. J., Dhiman, H. K., Klein-Seetharaman, J. and Bahar, I. (2006) Predisposition of the dark state of rhodopsin to functional changes in structure. Proteins. 65, 970-983
Rubenstein, E. M., McCartney, R. R. and Schmidt, M. C. (2006) Regulatory domains of Snf1-activating kinases determine pathway specificity. Eukaryot Cell. 5, 620-627

Elbing, K., Rubenstein, E. M., McCartney, R. R. and Schmidt, M. C. (2006) Subunits of the Snf1 kinase heterotrimer show interdependence for association and activity. J Biol Chem. 281, 26170-26180

Delfino, F. J., Shaffer, J. M. and Smithgall, T. E. (2006) The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase. Biochem J. 399, 141-150

Skvorak, K., Vissel, B. and Homanics, G. E. (2006) Production of conditional point mutant knockin mice. Genesis. 44, 345-353

Homanics, G. E., Skvorak, K., Ferguson, C., Watkins, S. and Paul, H. S. (2006) Production and characterization of murine models of classic and intermediate maple syrup urine disease. BMC Med Genet. 7, 33

Constantinescu, D., Gray, H. L., Sammak, P. J., Schatten, G. P. and Csoka, A. B. (2006) Lamin A/C expression is a marker of mouse and human embryonic stem cell differentiation. Stem Cells. 24, 177-185

Guerriero, C. J., Weixel, K. M., Bruns, J. R. and Weisz, O. A. (2006) Phosphatidylinositol 5-kinase stimulates apical biosynthetic delivery via an Arp2/3-dependent mechanism. J Biol Chem. 281, 15376-15384

Miedel, M. T., Weixel, K. M., Bruns, J. R., Traub, L. M. and Weisz, O. A. (2006) Posttranslational cleavage and adaptor protein complex-dependent trafficking of mucolipin-1. J Biol Chem. 281, 12751-12759

Leeman, R. J., Lui, V. W. and Grandis, J. R. (2006) STAT3 as a therapeutic target in head and neck cancer. Expert Opin Biol Ther. 6, 231-241

de Souza, A. J. and Kane, L. P. (2006) Immune regulation by the TIM gene family. Immunol Res. 36, 147-155

Knickelbein, J. E., de Souza, A. J., Tosti, R., Narayan, P. and Kane, L. P. (2006) Cutting edge: inhibition of T cell activation by TIM-2. J Immunol. 177, 4966-4970

Chen, L., Arora, M., Yarlagadda, M., Oriss, T. B., Krishnamoorthy, N., Ray, A. and Ray, P. (2006) Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide. J Immunol. 177, 2373-2383

Yang, Q., Goding, S. R., Hokland, M. E. and Basse, P. H. (2006) Antitumor activity of NK cells. Immunol Res. 36, 13-25

Clifton, D. R., Nolder, C. L., Hughes, J. L., Nowalk, A. J. and Carroll, J. A. (2006) Regulation and expression of bba66 encoding an immunogenic infection-associated lipoprotein in Borrelia burgdorferi. Mol Microbiol. 61, 243-258

Sheridan, B. S., Khanna, K. M., Frank, G. M. and Hendricks, R. L. (2006) Latent virus influences the generation and maintenance of CD8+ T cell memory. J Immunol. 177, 8356-8364

Vella, L. A. and Finn, O. J. (2006) Innate and adaptive immunity in lung cancer. Novartis Found Symp. 279, 206-212; discussion 213-205, 216-209

Egloff, A. M., Vella, L. A. and Finn, O. J. (2006) Cyclin B1 and other cyclins as tumor antigens in immunosurveillance and immunotherapy of cancer. Cancer Res. 66, 6-9

Chalovich, E. M., Zhu, J. H., Caltagarone, J., Bowser, R. and Chu, C. T. (2006) Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells. J Biol Chem. 281, 17870-17881

Tomko, R. J., Jr., Bansal, P. and Lazo, J. S. (2006) Airing out an antioxidant role for the tumor suppressor p53. Mol Interv. 6, 23-25, 22

Knickelbein, J. E., de Souza, A. J., Tosti, R., Narayan, P. and Kane, L. P. (2006) Cutting edge: inhibition of T cell activation by TIM-2. J Immunol. 177, 4966-4970

Chandra, D., Jia F, Liang J, Peng Z, Suryanarayanan A, Werner DF, Spigelman I, Houser CR, Olsen RW, Harrison NL, Homanics GE (2006) GABAA receptor alpha4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol. Proc Natl Acad Sci U S A 103:15230-15235

Jun, S., Becker, J.S., Yonkunas, M., Coalson, R., Saxena, S. (2006) Unfolding of alanine-based peptides using electron spin resonance distance measurements. Biochemistry, 45(38),11666-11673.

2005

Ferris, R. L., Martinez, I., Sirianni, N., Wang, J., Lopez-Albaitero, A., Gollin, S. M., Johnson, J. T. and Khan, S. (2005) Human papillomavirus-16 associated squamous cell carcinoma of the head and neck (SCCHN): a natural disease model provides insights into viral carcinogenesis. Eur J Cancer. 41, 807-815

Wang, E. C., Lee, J. M., Ruiz, W. G., Balestreire, E. M., von Bodungen, M., Barrick, S., Cockayne, D. A., Birder, L. A. and Apodaca, G. (2005) ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells. The Journal of Clinical Investigation. 115, 2412-2422

Wilson, A., Zhou, W., Champion, H. C., Alber, S., Tang, Z. L., Kennel, S., Watkins, S., Huang, L., Pitt, B. and Li, S. (2005) Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo. Mol Ther. 12, 510-518

O'Keefe, S. J., Lee, R. B., Li, J., Stevens, S., Abou-Assi, S. and Zhou, W. (2005) Trypsin secretion and turnover in patients with acute pancreatitis. American Journal of Physiology. 289, G181-187

Zhou, W., Heiney, P. A., Fan, H., Smalley, R. E. and Fischer, J. E. (2005) Single-walled carbon nanotube-templated crystallization of H2SO4: direct evidence for protonation. Journal of the American Chemical Society. 127, 1640-1641

Oriss, T. B., Ostroukhova, M., Seguin-Devaux, C., Dixon-McCarthy, B., Stolz, D. B., Watkins, S. C., Pillemer, B., Ray, P. and Ray, A. (2005) Dynamics of dendritic cell phenotype and interactions with CD4+ T cells in airway inflammation and tolerance. J Immunol. 174, 854-863

Brisson, M., Nguyen, T., Wipf, P., Joo, B., Day, B. W., Skoko, J. S., Schreiber, E. M., Foster, C., Bansal, P. and Lazo, J. S. (2005) Redox regulation of Cdc25B by cell-active quinolinediones. Molecular Pharmacology. 68, 1810-1820
Saini, S. P., Mu, Y., Gong, H., Toma, D., Uppal, H., Ren, S., Li, S., Poloyac, S. M. and Xie, W. (2005) Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice. Hepatology . 41, 497-505

Uppal, H., Toma, D., Saini, S. P., Ren, S., Jones, T. J. and Xie, W. (2005) Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice. Hepatology. 41, 168-176

Smedley, J. G., 3rd, Jewell, E., Roguskie, J., Horzempa, J., Syboldt, A., Stolz, D. B. and Castric, P. (2005) Influence of pilin glycosylation on Pseudomonas aeruginosa 1244 pilus function. Infection and Immunity. 73, 7922-7931

McCartney, R. R., Rubenstein, E. M. and Schmidt, M. C. (2005) Snf1 kinase complexes with different beta subunits display stress-dependent preferences for the three Snf1-activating kinases. Curr Genet. 47, 335-344

de Souza, A. J., Oriss, T. B., O'Malley K, J., Ray, A. and Kane, L. P. (2005) T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation. Proc Natl Acad Sci U S A. 102, 17113-17118

Steele, C., Rapaka, R. R., Metz, A., Pop, S. M., Williams, D. L., Gordon, S., Kolls, J. K. and Brown, G. D. (2005) The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog. 1, e42

Zheng, M., Ramsay, A. J., Robichaux, M. B., Norris, K. A., Kliment, C., Crowe, C., Rapaka, R. R., Steele, C., McAllister, F., Shellito, J. E., Marrero, L., Schwarzenberger, P., Zhong, Q. and Kolls, J. K. (2005) CD4+ T cell-independent DNA vaccination against opportunistic infections. J Clin Invest. 115, 3536-3544

Prabhakaran, K., Sheridan, B. S., Kinchington, P. R., Khanna, K. M., Decman, V., Lathrop, K. and Hendricks, R. L. (2005) Sensory neurons regulate the effector functions of CD8+ T cells in controlling HSV-1 latency ex vivo. Immunity. 23, 515-525

Yu, X., Caltagarone, J., Smith, M. A. and Bowser, R. (2005) DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells. J Alzheimers Dis. 8, 7-21

Chandra, D., Korpi, E. R., Miralles, C. P., De Blas, A. L. and Homanics, G. E. (2005) GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines. BMC Neurosci. 6, 30

Li, L., Geng, X., Yonkunas, M., Su, A., Densmore, E., Tang, P., Drain, P. (2005) Ligand-dependent linkage of the ATP site to inhibition gate closure in the KATP channel. Journal of General Physiology, 126(3), 285-299.

2004

Vodovotz, Y., Kim, P. K., Bagci, E. Z., Ermentrout, G. B., Chow, C. C., Bahar, I. and Billiar, T. R. (2004) Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies. Current Molecular Medicine. 4, 753-762

Oguri, T., Nemoto, K., Bansal, P., Wipf, P. and Lazo, J. S. (2004) Induction of Cdc25B expression by epidermal growth factor and transforming growth factor-alpha. Biochemical Pharmacology. 68, 2221-2227

Bansal, P., Sun, M. and Sclabassi, R. J. (2004) Simulation and extraction of single-trial evoked potentials. Conf Proc IEEE Eng Med Biol Soc. 1, 200-203

Xie, W., Uppal, H., Saini, S. P., Mu, Y., Little, J. M., Radominska-Pandya, A. and Zemaitis, M. A. (2004) Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism. Drug Discovery Today. 9, 442-449

Saini, S. P., Sonoda, J., Xu, L., Toma, D., Uppal, H., Mu, Y., Ren, S., Moore, D. D., Evans, R. M. and Xie, W. (2004) A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification. Molecular Pharmacology. 65, 292-300

Smedley, J. G., 3rd and McClane, B. A. (2004) Fine mapping of the N-terminal cytotoxicity region of Clostridium perfringens enterotoxin by site-directed mutagenesis. Infection and Immunity. 72, 6914-6923

Smedley, J. G., 3rd, Fisher, D. J., Sayeed, S., Chakrabarti, G. and McClane, B. A. (2004) The enteric toxins of Clostridium perfringens. Reviews of Physiology, Biochemistry and Pharmacology. 152, 183-204

Rader, A. J., Anderson, G., Isin, B., Khorana, H. G., Bahar, I. and Klein-Seetharaman, J. (2004) Identification of core amino acids stabilizing rhodopsin. Proc Natl Acad Sci U S A. 101, 7246-7251

Ellis, M. A., Miedel, M. T., Guerriero, C. J. and Weisz, O. A. (2004) ADP-ribosylation factor 1-independent protein sorting and export from the trans-Golgi network. J Biol Chem. 279, 52735-52743

Ellis, M. A., Miedel, M. T., Guerriero, C. J. and Weisz, O. A. (2004) ADP-ribosylation factor 1-independent protein sorting and export from the trans-Golgi network. J Biol Chem. 279, 52735-52743

Kanno S., Kim P.K., Sallam K., Lei J., Billiar T.R., Shears, L.L. 2nd. (2004) Nitric oxide facilitates cardiomyogenesis in mouse embryonic stem cells. Proc Natl Acad Sci U S A. 101, 12277-81

Chen, Y., Helmus, R., McClane, B., Hoffman, R., Watkins, S., Wehrli, T. and Gupta, P. (2004) Use of a Clostridium perfringens vector to express high levels of SIV p27 protein for the development of an oral SIV vaccine. Virology. 329, 226-233

Strachan, G. D., Morgan, K. L., Otis, L. L., Caltagarone, J., Gittis, A., Bowser, R. and Jordan-Sciutto, K. L. (2004) Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein. Biochemistry. 43, 12113-12122

Yonkunas M.J., Xu, Y., Tang, P. (2004) Anesthetic Interaction with Ketosteroid Isomerase: Insights from Molecular Dynamics Simulations. Biophysical Journal, 89(4), 2350-2356.

2003

Yuan, X., Ma, Z., Zhou, W., Niidome, T., Alber, S., Huang, L., Watkins, S. and Li, S. (2003) Lipid-mediated delivery of peptide nucleic acids to pulmonary endothelium. Biochemical and Biophysical Research Communications. 302, 6-11

Putnam, A.J., Cunningham, J.J., Pillemer, B.B.L., and Mooney, D.J. (2003). “External mechanical strain regulates membrane targeting of Rho GTPases by controlling microtubule assembly,” Am. J. Physiol. Cell Physiol. 284:C627-C639.

Andresen, B. T., Linnoila, J. J., Jackson, E. K. and Romero, G. G. (2003) Role of EGFR transactivation in angiotensin II signaling to extracellular regulated kinase in preglomerular smooth muscle cells. Hypertension. 41, 781-786

2002

Rhodes, M. E., Balestreire, E. M., Kenneth Czambel, R. and Rubin, R. T. (2002) Estrous cycle influences on sexual diergism of HPA axis responses to cholinergic stimulation in rats. Brain research bulletin. 59, 217-225

Zhou, W., Yuan, X., Wilson, A., Yang, L., Mokotoff, M., Pitt, B. and Li, S. (2002) Efficient intracellular delivery of oligonucleotides formulated in folate receptor-targeted lipid vesicles. Bioconjugate Chemistry. 13, 1220-1225